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Brimrose is proud to introduce the Luminar 4090. This new AOTF-NIR spectrometer is non-destructive, rapid test device for determining BU, designed to easily mount to blenders and to allow customers to move the unit from blender to blender. The technique has been proven to prevent over or under blending, providing manufacturers with total control over the process.
Proper blending is vital to assure batch uniformity and the integrity of drug products. It is important that the Active Pharmaceutical Ingredient (API), excipients, and lubricants in each batch are uniform and homogeneous. A batch that is not fully blended can affect bio-availability in the end product and potentially harm the consumer.
The most common method of blending uniformity (BU) is through the use of timing and random sampling. Traditionally, the blend is run for a certain amount of time with samples taken and run through an HPLC to confirm proper ratios.
Timing methods with random sampling results in increased blend time, slower product turnovers, and waste product.
Spectral Range Options | 1100-2300 nm |
Measurement Modes | Diffuse Reflectance |
Spectral Resolution | 2-10 nm |
Wavelength Accuracy | ± 0.5 nm |
Wavelength Repeatability | ± 0.01 nm over more than 5 years’ service |
Wavelength Increment | Software Selectable 1-10 nm |
Ambient Light Rejection | > 106 |
S/N at 70% Range | < 30μabs, for <5 seconds integration time |
Photometric Range | 3.5 AU |
Linearity | Better than 0.15% |
Sampling Speed | 16,000 wavelength/sec |
Sampling Area | 3-10 mm (custom) |
Sampling Distance | 20-100 mm (custom) |
Internal Diagnostic | 10 Built-in monitoring sensors |
Power Supply | 30Watts, 14.8V Lithium Ion Battery (~6hrs with 140Wh capacity) |
Communication | TCP/IP and Wireless |
Software Package | Windows-based analytical software for data acquisition |
Enclosure | Environmentally sealed NEMA IP65 |
Communication | Wireless, OPC UA, Modbus (Serial or TCP), I/O with 4-20mA, TCP/IP Ethernet |
Unit Weight | 10 lbs |
Unit Dimensions (W x H x D) | 200 mm x 150 mm x 81 mm |