Blending Uniformity
KNOW WHEN TO STOP BLENDING
Brimrose solid state, robust components enable our spectrometers to be integrated directly to the blender for real-time measurement. Our spectrometers determine when blending is complete, minimizing production time, and cost to market of your products.
PROPER BLENDING
Proper blending is vital to assure batch uniformity and the integrity of drug products. It is important that the Active Pharmaceutical Ingredient (API), excipients, and lubricants in each batch are uniform and homogenous. A batch that is not fully blended can affect bioavailability in the end product and potentially harm the consumer.
TIMING AND RANDOM SAMPLING
The most common method of blending uniformity (BU) is through the use of timing and random sampling. Traditionally, the blend is run for a certain amount of time with samples taken and run through an HPLC to confirm proper ratios. Timing methods with random sampling results in increased blend times, slower product turnovers, and wasted product.
REQUEST QUOTE AND / OR WHITE PAPER
Brimrose Luminar 5030 AOTF-NIR Spectrometer for Blending Uniformity in Pharmaceutical Industry
A BETTER METHOD
AOTF-NIR Spectrometers are non-destructive, rapid test devices for determining BU. The technique has been proven to prevent over or under blending, providing manufacturers with total control over the process.
Monitor Blending for Every Batch: The flexible design allows you to move the unit from blender to blender.
Control Your Blending: Continuous monitoring provides accurate control of your blend.
Brimrose Luminar 4030 Free Space AOTF-NIR Spectrometer for Online Blending Control
A PROVEN BENEFIT
Successful implementation of a Brimrose AOTF-NIR spectrometer results in:
Ensured Quantitative & Qualitative Accuracy
Faster Product Turnover
Reduced Blend Time
Less Waste Product
Assured Uniformity
